Burning Mouth Syndrome-A Report of 3 Cases

Mingi Chan-Liao

Dept. of Anesthesia, Jen-Ai Hospital, Tali, Taichung, Taiwan

The burning mouth syndrome(BMS) is a relatively common intraoral disorder affecting women seven times more frequently than men. It is characterized by burning and painful sensations of the mouth in the absence of significant mucosal abnormalities.

The pain is typically reported at the anterior part of the tongue, the anterior hard palate and the lip. We report our recent experience in treating 3 cases of BMS. All were post-menopausal women and treated mainly with a series of stellate ganglion blocks plus antiderpressants except for Case 2 who in addition received low-level laser therapy but in vain.

Typically they had different manifestations and different outcomes after treatment. Case 1 and 2 could be classified(Tab.2) as type 2 (continuous) BMS and Case 3 as type 3 (intermittent) BMS based on diurnal fluctuations of symptoms according to Lamey and Lewis. Following basically similar treatment for 2 weeks~2months, Case 1 had total relief of pain, Case 2 had only partial improvement but Case 3 experienced no improvement at all. BMS with many other confusing synonyms(Tab.1) is a difficult disease for both patients and pain clinicians. Because its etiology and pathophysiology are still unknown, evaluation should be followed in a stepwise fashion and management(Fig.1) focused on correcting suspected causative factors(local, systemic or psychologic). Generally it is believed that psychologic factors predominate in the etiology of BMS. It is unclear whether psychologic factors predispose patients to BMS or whether BMS predisposes them to psychologic disorders but treatment with low-dose antidepressants is always indicated.

Tab.1 Synonyms of Burning Mouth Syndrome

Glossalgian Syndorme

Glossodynia

Glossopyrosis

Stomatodynia

Stomatopyrosis

Oral dysesthesia

Denture sore mouth


Tab.2 Classification of 3 Subtypes of BMS

Type

Other Linked Etiology

Burning Sensation

1

Nutritional deficiencies

Symptom-free on waking

2

Chronic anxiety

Continuous

3

50% emotional instability

50% food allergies, Intermittent

(Lamey and Lewis 1989)

Tab3. Summary of 3 cases with intraoral burning

 

Age

Sex

Meno-pause

Signs and Symptoms

Treatment

Outcome

Remarks

Case1

70

F

¡Ï

lIntermittent burning

lnormal mucosa

lstellate gl.block

(SGB)

lantidepressant

lbenzodiazepine

Cure

Dramatic

 

Improvement

After SGB

Case2

66

F

¡Ï

lInsomnia

lXerostomia

lDepression

lCancerophobia

lstellate gl. Block

lantidepressant

llow-level laser

Sx unresolved

Patient abandoned further Tx after 2 wks

Case3

58

F

¡Ï

lXerostomia

lDepression

lHalitosis

lstellate gl. Block

lantidepressant

lmexiletine

Partial

improvement

lDiabetic

ldenture

 


Fig1 A Clinical Protocol for

Evaluation and Management of Burning Mouth Syndrome

Medical, dental, psychological history

â

Physical exam of oral mucosa and dentition

  Exam of denture design and occlusion

                                                                                                               

 

Abnormal                                                                Normal

â                                                                      â

Laboratories/treatment                                    Laboratory evaluations

Directed by diagnosis                                     fasting blood suger, fungal

Geographic tongue                                          cultures, complete blood

Candidiasis                                                     patch test

Lichen planus

Xerostomia

Contact stomatitis                            Positive                           Negative

                        Treatment directed by              Eliminate oral irritants

                        Lab findings                            Eliminate drugs

                                                                        Empiric anticandidal

                                                                        Nutritional, estrogen

                                                                        Therapy

                                                                                               

 

Consider chronic pain therapy

Antidepressants

Benzodiazepines

Topical capsaicin

Clonazepam

Laser