原資訊網分類
SOTA OMOIGUI`S PAIN DRUG HANDBOOK分類
成份名
常見之商品名
疼痛常用劑量
適應症
一級交互作用
二級交互作用
三級交互作用
四級交互作用
Aspirin, Acetaminophen
Nonopioid Analgesics
Acetaminophen
Panadol, Panamax
PO: 325-650mg q4h, Max 2.6g/day

錠劑,膠囊,糖衣錠,糖漿劑,

內服液劑,酏劑,栓劑

退燒、止痛(緩解頭痛、牙痛、咽喉痛、關節痛、神經痛、肌肉酸痛、月經痛) 
 
terfenadine
alcohol, charcoal, isoniazid,oral contraceptive agents, phenobarbital, phenytoin, propranolol, sulfinpyrazone, chloramphenicol, lamotrigine, warfarin, zidovidine
 
Aspirin, Acetaminophen
Nonopioid Analgesics
Aspirin
Aspirin
325-650mg q4h, Max 6g/day 錠劑,膠囊劑,膜衣錠,腸溶劑,栓劑
退燒、止痛(緩解頭痛、牙痛、咽喉痛、關節痛、神經痛、肌肉酸痛、月經痛)                                                                                                        
heparin, methotrexate, warfarin
acetazolamide, alcohol, antacid, methylprednisolone, other corticosteroids, captopril, chlorpropamide, sulfinpyrazone, valproic acid
charcoal, dipyridamole, ginkgo, griseofulvin, nitroglycerin, oral contraceptive agent, fluxetine, furosemide, indomethacin, insulin, niacin, penicillin-G, propranolol,  spironolactone
ascorbic acid, phenytoin
 other NSAID
 
Acemetacin
Acemet, Rantudil
60-120mg tid 膠囊劑
風濕性關炎、退化性關節炎(骨關節炎)、僵直性脊椎炎、痛風、肌肉炎、腱鞘炎、滑囊炎                                
 
 
 
 
 other NSAID
Nonopioid Analgesics
Celecoxib
Celebrex
200mg qd or 100mg bid 膠囊劑
緩解骨關節炎之症狀與徵兆、緩解成人類風濕性關節炎之症狀與徵兆
 
 
 
 
 
Nonopioid Analgesics
Choline salicylate
Trilisate
435-870mg q4h 錠劑
風濕性關節及其他關節病症狀的減輕 
 
 
 
 
 other NSAID
Nonopioid Analgesics
Diclofenac
Cataflam, Voltaren
50 mgbid-qid, Max 200mg/day 糖衣錠,錠劑,腸溶錠,注射劑,栓劑
下列疾患之消炎、鎮痛作用:慢性風濕性關節炎、變形關節症、變形性脊髓症、腰痛、腱鞘炎、神經痛                           
 
cyclosporine
 
 
 
Nonopioid Analgesics
Diflunisal
Dolobid
1g (20mg/Kg) then 500mg (10mg/Kg) bid-tid 錠劑,膠囊劑,膜衣錠
骨關節炎(退化性關節病症)外傷後肌肉骨骼扭傷及勞損、扭傷而引起之疼痛、生產女陰切開後之疼痛、骨科及牙科手術後之疼痛               
 
 
oxazepam
 
 other NSAID
 
Etofenamate
Traumon, Relex
apply tid-qid daily 外用凝膠劑,乳膏劑
肌肉性風濕症、上腕肩胛關節周圍炎、坐骨神經、腰痛、腱鞘炎、粘液囊炎   
 
 
 
 
 other NSAID
Nonopioid Analgesics
Etodolac
Lonine
200-400mg q6-12h 膜衣錠,膠囊劑
疼痛之短期療法                            
 
 
 
 
 
Nonopioid Analgesics
Fenoprofen calcium
Fenopron
200mg (4mg/kg) q4-6h 膠囊劑
鎮痛                                 
 
 
phenobarbital
 
 other NSAID
 
Fenbufen
Cinopal
200mg q4-6h 膜衣錠,錠劑,膠囊劑
骨關節炎、類風濕性關節炎、關節強性脊椎炎、急性痛風關節炎及術後與外傷性疼痛                                   
 
 
 
 
 other NSAID
Nonopioid Analgesics
Flurbiprofen
Furofen
Arthritis: 200-300mg/daily in 2-4divided doses 糖衣錠,錠劑,膜衣錠 
下列疾患及症狀之鎮痛消炎:慢性關節風濕症、變形性關節症、腰痛症、齒髓炎、齒根膜炎、拔牙及齒科領域小手術後之鎮痛、消炎              
 
 
 
 
 other NSAID
Nonopioid Analgesics
Ibuprofen
Motrin, Brufen
200-800mg (8-16mg/kg) q6h, Max 4.2g/day 錠劑,糖衣錠,膠囊劑,內服顆粒劑,糖漿,懸液劑,乳膏劑,針劑
下列諸症狀之消炎、鎮痛、風濕性關節痛、風濕性關節炎、神經痛、神經炎、背腰痛、手術、外傷後之消炎、鎮痛
 
digoxin, phenytoin, warfarin
baclofen
 
 other NSAID
Nonopioid Analgesics
Indomethacin
Indocin
25-50mg (0.5-1.0mg/kg) bid-qid, Max 200mg/day 膠囊劑,腸溶錠,糖衣錠,軟膏劑外用凝膠劑,栓劑,乳膏劑,外用液劑,貼布,噴劑
關節炎、僂麻質斯、變形性關節症等炎症之消炎、鎮痛、解熱以及其他疾患之消炎
 
phenylpropanolamine, probenecid, bendroflumethiazide, captopril, gentamicin, lithium, prazosin, propranolol, triamterene, warfarin
aluminum hydroxide, aspirin, cimetidine, nitroglycerin, cyclophosphamide, furosemide, hydralazine, penicillamine
 
 other NSAID
Nonopioid Analgesics
Ketoprofen
Profenid, Ketoprofen
25-50mg (0.5-1.0mg/kg) q6-8h, Max 300mg/day 糖衣錠,膠囊劑,外用凝膠劑,栓劑,針劑
鎮痛、消炎(風濕樣關節炎、骨關節痛、腰痛、背痛、外傷及手術後之疼痛)之緩解                                   
 
methotrexate
 
 
 other NSAID
Nonopioid Analgesics
Ketorolac
Keto
10-20mg star then 10mg q4-6h, Max 40mg/day 膜衣錠,注射劑,點眼液劑
疼痛之短期療法                            
 
 
 
 
 other NSAID
Nonopioid Analgesics
Meclofenamate
Meclomen
200-300mg (4-6mg/kg)/daily in 3-4 divided doses, Max 400mg/day 膠囊劑
解除輕及中度疼痛,急性與慢性風濕性關節炎,骨關節炎之症狀與徵象,關節粘連性脊椎炎,月經疼痛、經血過多。
 
 
 
 
 other NSAID
Nonopioid Analgesics
Mefenamic acid
Ponstan
500mg (10mg/kg) then 250mg (5mg/kg) q6h, Max 1000mg/day 膠囊劑,膜衣錠,錠劑
神經炎、神經痛、關節炎                         
 
 
 
 
 other NSAID
 
Meloxicam
Mobic
Arthritis: 7.5-15mg qd 錠劑
類風濕性關節炎、骨關節炎、及僵直性脊椎炎之症狀治療。                                              
 
 
 
 
 other NSAID
 
Mepirizole
Mebron
150-450mg in 2-4 divided doses 膜衣錠,腸溶錠,糖衣錠,錠劑
下述症狀之鎮痛、消炎:腰痛症、神經痛、急性上氣管炎(扁桃炎、咽、喉頭炎)膀胱炎、齒髓炎、手術及外傷後之鎮痛及消炎                
 
 
 
 
 other NSAID
Nonopioid Analgesics
Nabumetone
Relifexn, Nabuton
1000-2000mg daily (20-40 mg/kg/day) in 1-2 divided doses, Max 1000mg/day 膜衣錠,錠劑 
退化性關節炎及風濕性關節炎之消炎鎮痛                 
 
 
 
 
 other NSAID
Nonopioid Analgesics
Naproxen
Naposin
500mg (10mg/kg) then 250mg (5mg/kg) tid-qid, Max 1.25g/day 錠劑,膠囊劑,栓劑,膜衣錠,長效持續發釋錠
急慢性風濕關節炎、關節局部腫脹、強直性脊椎關節炎、脊椎炎、椎關節炎、關節周圍炎、上腕肩甲骨炎及骨骼肌不適之粘液囊炎、腱鞘炎之消炎、鎮痛解熱   
 
gold sodium thiomalate
cholestyramine, valproic acid
 
 other NSAID
 
Nefopam
Paton
IM 20mg q4-6h, slow IV 10-20mg q4-6h, Max 120mg/day 注射劑,膜衣錠 ,錠劑 
鎮痛                                 
 
 
 
 
 other NSAID
 
Nimesulide
Nimed, Mesulid
100mg bid, Max 400mg/day 錠劑
1.治療關節炎之症狀  2.治療肌腱炎、滑襄炎、肌肉扭傷  3.手術後疼痛、月經痛及癌症疼痛之緩解
 
 
 
 
 other NSAID
Nonopioid Analgesics
Piroxicam
Feldene
20-40mg (0.4-0.8 mg/kg) daily in 1-2 divided doses 膠囊劑,針劑,凝膠劑
類風濕性關節炎、骨關節炎(關節痛、退化性關節炎)僵直性脊椎炎、急性肌肉骨骼損傷、急性痛風、和原發性痛經,幼年型慢性關節炎          
 
 
 
 
 other NSAID
 
Rofecoxib
Vioxx
Osteoarthritis: 12.5mg qd, Max 25mg/day Acute pain and dysmenorrhea: 50mg RA: 25-50mg/day 錠劑
骨關節炎之短期及長期症狀治療,緩解疼痛,治療原發性經痛
 
 
 
 
 
Nonopioid Analgesics
Salsalate
Disalcid
2-4g (40-80mg/kg) daily in 2-3 divided doses 膜衣錠,錠劑 
風濕性關節炎、骨關節炎                         
 
 
 
 
 other NSAID
Nonopioid Analgesics
Sulindac
Dometon, Clinoril
150-200mg (3-4mg/kg) bid, Max 400mg/day 錠劑
骨關節炎、風濕性關節炎、關節黏連性脊椎炎、急性痛風關節炎        
 
 
 
 
 other NSAID
 
Tenoxicam
Tilcotil
RA: 20mg/day Acutegouty arthritis: IM/IV 40mg/day×2day, 20mg/day×5day 膜衣錠
風濕性關節炎、變性關節疾病、關節黏連性脊椎炎、關節外疾病、腱炎、滑囊炎、肩部及臀部的關節周圍炎、拉傷、扭傷、扭傷、急性痛風          
 
 
 
 
 other NSAID
 
Tiaprofenic acid
Surgam
200mg tid 錠劑
消炎、鎮痛                               
 
 
 
 
 
Nonopioid Analgesics
Tolmetin sodium
Tolmetin
400-600mg (8-12 mg/kg) tid, Max 2000mg/day 膠囊劑,錠劑
風濕性關節炎症狀(關節紅腫、關節痛、肌肉僵硬)之緩解            
 
 
 
 
Anticonvulsants
Anticonvulsants
Carbamazepine
Tegretol, Tegretol CR
Pain: initial dose 100mg (2mg/kg), normal dose range 600-1600mg/day 錠劑,持續性藥效錠,膜衣錠,內服液劑,咀嚼錠,緩釋錠
癲癇(大發作、精神運動發作)三叉神經痛                 
charcoal, erythromycin, clozapine
cimetidine, danazol, felbamate, isoniazid, metronidazole, propoxyphene, verapamil, cyclosporine, doxycycline, haloperidol, lithium, theophylline, valproic acid
desipramine, hydrochlorothiazide, isotretinoin, metoclopramide, niacinamide, oral contraceptive agents, phenobarbital, terfenadine, bupropion, clonazepam, ethosuximide, pancuronium, phenytoin
 
Anticonvulsants
 
Clonazepam
Rivotril
Pain: initial dose 0.25mg bid, increasing to 1mg/day after 3 days, maintenance dose 1mg/day 錠劑
癲癇                                 
 
 
carbamazepine, phenelzine,valproic acid
primidone
Anticonvulsants
Anticonvulsants
Gabapentin
Neurontin
Maintenance: 900-1800 mg/day in 1-3 divided dose 膠囊劑
成人單純性及複雜性的局部發作之癲癇之輔助治療
 
 
 
 
Anticonvulsants
 
Lamotrigine
Lamictal
added to EIAED regimen without VPA: week 1 and 2: 50mg/day, week 3 and 4: 100mg/day (in two divided doses), usual maintenance dose: 300 to 500mg/day added to AED regimen containing VPA: week 1 and 2: 25mg every other day, week 3 and 4: 25mg/day usual maintenance dose: 100 to 400mg/day 錠劑,咀嚼錠
癲癇症及對其他抗癲癇藥無法滿意控制之局部癲癇、泛發性強直性陣攣性癲癇之輔助療法及LENNOX-GASTAUT徵候群。             
 
acetaminophen,sodium valproate
 
 
Anticonvulsants
Anticonvulsants
Phenytoin (Diphenylhydantoin)
Dilantin
Pain: 100-150mg (2-3mg/kg) bid-qid 注射劑,膠囊劑,錠劑 
癲癇(尤其是大發作、乍克森氏型發作、精神運動發作、其他痙攣性發作)   
cimetidine, disulfiram, dopamine, fluconazole
alcohol, allopurinol, amiodarone, carmustine, MTX, vinblastine, charcoal, chloramphenicol, chlorpheniramine, cyclosporine, dexamethasone, diazoxide, felbamate, fluoxetine, folic acid, ibuprofen, isoniazid, methoxsalen, nifedipine, omeprazole, phenylbutazone, pyridoxine, rifampin, sucralfate, sulfamethizole, ticlopidine, trimethoprim, valproic acid, dicumarol, digitalis, disopyramide, doxycycline, ergocalciferol, metocurine, primidone, quinidine, theophylline
antacid, carbamazepine, chlorpromazine, ciprofloxacin, diazepam, Ethosuximide, imipramine, influenza virus vaccine, levodopa, levothyroxine, methylphenidate, metronidazole, nitrofurantoin, oral contraceptive agents, phenobarbital, trazodone , acetaminophen, furosemide, halothane, insulin, lithium, meperidine, metyrapone, mexiletine
acetazolamide, aspirin
 
Anticonvulsants
Valproic acid
Depakine, Convulex
Pain: 250-2000mg (5-15mg/kg)/day hs or tid, Max 40mg/kg/day Migraine prophylaxis: PO 250mg bid 軟膠囊劑,腸溶錠,持續性藥效膜衣錠
癲癇之大發作、小發作、混合型及顳葉癲癇                
 
aspirin, carbamazepine, erythromycin, felbamate, phenobarbital, phenytoin
antacid, amitriptyline, chlorpromazine, cimetidine, clonazepam, fluoxetine, isoniazid, naproxen, ethosuximide, lamotrigine, naproxen
 
Antidepressants
Antidepressants
Amitriptyline
 Laroxyl, Tryptanol, Limbitrol
Pain: initial 10-25mg (0.2-1.5mg/kg)/day, maintenance 10-150mg/day (0.2-3mg/kg) Migraine prophylaxis/ Tension headache: PO 25-75mg (0.5-1.5mg/kg)/day 糖衣錠,注射劑,膠囊劑,錠劑,長效錠 
憂鬱病                                
 
fluconazole, alcohol
chlordiazepoxide, disulfiram, methyldopa, morphine, valproic acid
 
Antidepressants
 
Clomipramine
Anafranil
Depression/ Chronic pain 100-250mg/day 膠囊劑,錠劑,糖衣錠,膜衣錠
憂鬱病,各種病因及症狀的憂鬱狀態,強迫症,恐懼症,驚懼發作伴隨發作性睡病的猝倒症                                
 
 
 
 
 
Antidepressants
Doxepin
Sinequan, Ichderm
Pain: initial 25-50mg (0.5-1.0mg/kg)/day, maintenance 25-150mg/day (0.5-3mg/kg) hs Migraine prophylaxis/ Tension headache: 25-50mg (0.5-1.0mg/kg)/day 膠囊劑,乳膏劑
焦慮狀態、憂鬱病                            
 
cholestyramine, tolazamide
propoxyphene
 
Antidepressants
Antidepressants
Fluoxetine
Prozac
Pain: initial 5-20mg (0.1-0.4mg/kg)/day, maintenance 5-60mg/day (0.1-1.0mg/kg) in 1-2 divided dose 膠囊劑,錠劑,內服液劑
抑鬱症、暴食症、強迫症                         
tranylcypromine
cyproheptadine, marijuana, alprazolam, digoxin, lithium, nortriptyline, phenytoin, propranolol
Aspirin, clarithromycin, cyclosporine, tryptophan, buspirone, haloperidol, pimozide, trazodone, valproic acid, warfarin
alcohol
Antidepressants
Antidepressants
Imipramine
Tofranil
Pain: initial 25-100mg (0.5-2.0mg/kg)/day hs, maintenance 25-200mg/day (0.5-4.0mg/kg) hs 糖衣錠,膜衣錠,膠囊劑
憂鬱病、夜尿                              
 
cimetidine, epinephrine, nitroglycerin, tranylcypromine
bupropion, ethinyl estradiol, levodopa, liothyronine, lithium carbonate, methyltestosterone, reserpine, tobacco, meprobamate, phenytoin
 
Antidepressants
 
Maprotiline
Ludiomil
Chronic pain: initial 10-25mg/day, maintenance 25-75mg/day 膜衣錠,錠劑
抑鬱症                                 
 
 
 
 
Antidepressants
 
Moclobemide
Aurorix
Depression: 300-600mg in 2-3 divided dose 膜衣錠
憂鬱病
 
 
 
 
 
Antidepressants
Nortriptyline
Motival, Aventyl
Pain: initial 10-50mg (0.5-1.0mg/kg)/day hs, maintenance 10-150mg/day (0.2-3.0mg/kg) hs 錠劑,膠囊劑
憂鬱病 
 
fluoxetine, marijuana, terbinafine
charcoal, phenobarbital, rifampin
warfarin
 
Antidepressants
Paroxetine
Seroxat
Pain: initial 10-20mg/day qd, maintenance 10-50mg/day qd 膜衣錠
憂鬱症、強迫症、恐慌症                        
 
dextromethorphan
cimetidine, zolpidem
 
 
Antidepressants
Sertraline
Zoloft
Pain: initial 25-50mg/day in the morning or evening, maintenance 50-200mg/day in the morning or evening 膜衣錠
憂鬱症、強迫症                            
 
 
 
 
Antidepressants
Antidepressants
Trazodone
Mesyrel, Reslin
Pain: initial 150mg/day in divided dose, maintenance 150-400mg/day in divided dose 膜衣錠,錠劑
治療各種型態之抑鬱症                         
 
 
fluoxetine, digoxin, phenytoin, warfarin
 
Tranquilizers-Hypnotics (Neuroleptics)
Anxiolytic
Alprazolam
Xanax
Panic disorder: 0.5-1mg tid day dose, range of 1-10mg daily has been used with mean doses of 5-6mg daily 錠劑
焦慮狀態
 
fluoxetine
 
 
Tranquilizers-Hypnotics (Neuroleptics)
 
Bromazepam
Lexotan
1.5-3mg tid 錠劑
焦慮狀態
 
 
 
 
Tranquilizers-Hypnotics (Neuroleptics)
 
Brotizolam
Lendormin
Insomnia: 0.25mg nightly, 05mg nightly may be required 錠劑
失眠症                                  
 
 
 
 
Tranquilizers-Hypnotics (Neuroleptics)
Anxiolytic
Chlordiazepoxide
Librium
Sedation: 5-10mg (0.1-0.2mg/kg) tid-qid 錠劑,膠囊劑,糖衣錠
焦慮狀態、急性酒精戒斷症候群                     
 
 
ketoconazole, amitriptyline
warfarin
 
Anxiolytic
Clonazepam
Rivotril
Neuropathic pain: initial 0.25mg bid, Max 1mg/day 錠劑
癲癇                                 
 
 
carbamazepine, phenelzine, valproic acid
primidone
 
Anxiolytic
Diazepam
Valium
Antispamodic: 5-10mg tid 錠劑,注射劑
焦慮狀態、失眠、肌肉痙攣                       
 
alcohol, cimetidine, ketamine, digoxin
aminophylline, disulfiram, fluoxetine, isoniazid, levodopa, omeprazole, oral contraceptive agents, propranolol, rifampin, tobacco, bupivacaine, gallamine, lithium, methadone, phenytoin, propofol
 
Tranquilizers-Hypnotics (Neuroleptics)
 
Estazolam
Eurodin
1-2mg hs 錠劑
失眠                                  
 
 
 
 
Tranquilizers-Hypnotics (Neuroleptics)
 
Flunitrazepam
Rohypnol
IM premedication: 0.02-0.03mg/kg, administered 1-2 hrs prior to anesthesia induction. IV local anesthesia supplementation: 0.5-2mg Oral Insomnia: 1-2mg nightly 錠劑,膠囊劑,注射劑
失眠                                 
 
 
 
 
Tranquilizers-Hypnotics (Neuroleptics)
Anxiolytic
Lorazepam
Ativan
Sedation: 2-3mg bid or tid  Antiemetic: 1-2mg bid-tid 錠劑,注射劑
焦慮失眠                                
 
 
probenecid
 
Tranquilizers-Hypnotics (Neuroleptics)
Anxiolytic
Midazolam
Dormicum
Premedication: 0.25-1.0mg/kg (20-40mg) 膜衣錠,注射劑
口服:睡眠障礙和各類不眠症、外科、診斷過程前的鎮靜給藥。針劑:知覺鎮靜、急救加護病房鎮靜、麻醉誘導及維持、手術前給藥                     
 
erythromycin
thiopental
 
Tranquilizers-Hypnotics (Neuroleptics)
Neuroleptics
Haloperidol
Haldol
0.5-10mg (0.01-0.2mg/kg) in divided dose 錠劑,內服液劑,滴劑,注射劑
躁病、精神病狀態、噁心、嘔吐、攻擊性與破壞性之行為障礙、舞蹈病     
 
carbamazepine, rifampin, tacrine, lithium
fluoxetine, methyldopa, phenindione
 
Tranquilizers-Hypnotics (Neuroleptics)
phenothiazine
Chlorpromazine
Wintermin
Neuropathic and phantom limb pain: 25-100mg 1-5 times/day 糖衣錠,錠劑,膜衣錠,注射劑,糖漿劑
躁病、精神病狀態、噁心、嘔吐、攻擊性與破壞性之行為障礙 
guanethidine
alcohol, amphetamine, benztropine, diazoxide, lithium carbonate, captopril, diazoxide, meperidine, propranolol
antacid, levodopa, phenobarbital, piperazine, tobacco, insulin, phenytoin, valproic acid
 
 
phenothiazine
Fluphenazine decanoate
Fluphenzine decanoate
Pain: initial 0.5-1.0 mg (0.01-0.02mg/kg) q6-8h, maintenance 0.5-2.0mg (0.01-0.04mg/kg) q6-8h 注射劑
精神分裂症、和相關的精神病神經行為障礙                
 
 
clonidine
 
 
phenothiazine
Perphenazine
Triomin
Pain: 4-12mg (0.08-0.24mg/kg) hs 糖衣錠,錠劑,注射劑
神經病狀態、噁心、嘔吐                         
 
 
disulfiram
 
 
phenothiazine
Prochlorperazine
Novamin
Pain: 5-10mg tid-qid 糖衣錠,錠劑,注射劑
精神病狀態、噁心、嘔吐                         
 
polymyxin-B
 
 
 
phenothiazine
Promethazine
Pyrethia
Antiemetic/Sedative/Analgesic adjunct: IV/deep IM/PO 12.5-50mg 糖衣錠,注射劑
震顫麻痺、巴金生徵候群、麻醉前投藥、人工(藥物)冬眠、伴有感冒等上氣道炎之噴嚏、流鼻水、咳嗽、過敏性鼻炎、枯草熱、血管運動性浮腫、伴有皮膚疾患之搔癢(溼疹、皮膚炎、皮膚搔癢症、藥疹、中毒疹) 蕁痲疹、動暈病
 
 
 
 
Tranquilizers-Hypnotics (Neuroleptics)
 
Sulpirid
Dogmatyl
200mg-3200mg daily in 2-3divided doses. Lower doses may be adequate in acute, untreated patients, whereas higher doses may be required for chronic, severely ill schizophrinic patients 膜衣錠,注射劑,膠囊劑
精神病狀態、消化性潰瘍                         
 
 
 
 
Tranquilizers-Hypnotics (Neuroleptics)
 
Triazolam
Halcion
Hypnotic: 0.25mg hs 錠劑
不眠症
ketoconazole
 
 
 
Tranquilizers-Hypnotics (Neuroleptics)
 
Zolpidem
Stilnox
Hypnotic: 10mg hs 膜衣錠
失眠症                                  
 
 
paroxetine
 
Local Anesthetics
Local Anesthetic Agent
Bupivacaine
Marcaine
Infiltration, peripheral nerve block: 1-20ml (0.25-0.5% solution) Caudal: 37.5mg-150mg Brachial plexus block: 75-250mg  Epidural: Bolus 50-150mg Infusion 2-12ml/hr 注射劑
局部麻醉劑
 
ritodrine
diazepam
 
Local Anesthetics
Local Anesthetic Agent
Cocaine
Cocainse hydrochloridum
Topical: 1mg/kg (1-4% solution) Nasal: 1-2ml each nostril (1-4% solution)  Concentrations greater than 4% are not advisable and increase potential for systemic toxic reactions. Max safe dose: 1.5mg/kg 原料藥
局部麻醉劑
 
propranolol
 
 
 
Local Anesthetic Agent
Lidocaine
Lidocaine, Xylocaine
Local anesthesia Topical: 0.6-3.0mg/kg (2-4% solution) Infiltration/Peripheral nerve block: 0.5-5.0mg/kg (0.5-2.0% solution) Transtracheal: 80-120mg (2-3ml of 4% solution) Superior laryngeal nerve: 40-60mg (2-3ml of 2% solution on each side) Intravenous regional block: Upper extremities 200-250mg, Lower extremities 250-300mg Brachial Plexus block: 300-750mg  Stellate ganglion block: 10-20ml of 1% solution (100-200mg) with or without epinephrine 1:200,000  Epidural: Bolus 200-400mg (1-2% solution) Infusion 6-12ml/hr Spinal: bolus/infusion 50-100mg 注射劑,凍晶注射劑,凍膠,液劑
針劑:心室性不整律之急性治療。凍膠,液劑:表面麻醉
cimetidine
propranolol, amiodarone, succinylcholine
phenobarbital, procainamide
 
 
Local Anesthetic Agent
Lidocaine/Prilocaine
EMLA cream
Minor dermal procedures: Topical: apply 2.5g of Emla cream over 20-25 cm2 of intact skin and cover with occlusive dressing for at least 45 mins. Neonatal circumcision: Topical: apply 0.5-1.0g of EMLA cream over surgical site and cover with occlusive dressing for at liast 60-80 mins prior surgery. Major dermal procedures: Topical: Apply 2g of EMLA cream per 10cm2 of intact skin and cover with occlusive dressing for at least 2 hours. Max recommeded dose: 60g Max recommended area 10kg: 100cm2, 10-20kg: 600cm2, 20kg: 2000cm2 Max recommended duration: 4hrs 乳膏劑
與下列狀況有關的皮膚表面止痛:1.插針,如靜脈注射導管或抽血前;2.表皮外科處置;3.生殖器粘膜,如表皮外科處置前或浸潤麻醉前
 
 
 
 
 
Local Anesthetic Agent
Mepivacaine
Mepicaton
Infiltration: 50-400mg  Brachial plexus block: 300-750mg  Stellate ganglion block:10-20ml of 1%solution  Lumber sympathetic block: 10-15ml of 1% solution  Celiac plexus block: 20-25ml of 1%solution Epidural: Bolus 150-400mg, Infusion 6-12ml/hr 注射劑
牙科用麻醉劑
 
 
 
 
 
Local Anesthetic Agent
Prilocaine
 
Upper extremities: 200-250mg  Lower extremities: 250-300mg  Topical: See dosing information for EMLA  Infiltration/ peripheral nerve block: 1-15ml  Brachial plexus block: 300-750mg  Epidural: 10-25ml (1-2% solution) or 100-500mg. 乳膏劑
與下列狀況有關的皮膚表面止痛:1.插針,如靜脈注射導管或抽血前;2.表皮外科處置;3.生殖器粘膜,如表皮外科處置前或浸潤麻醉前
 
 
 
 
 
Local Anesthetic Agent
Procaine
Procaine
Infiltration:500mg of 0.5-2.0%solution Epidura: 10-25ml of 1-2% solution  Spinal: 0.5-2.0ml of 10% solution with glucose 5%. Max safe dose: 10mg/kg without epinephrine; 15mg/kg with epinephrine Systemic analgesia and pruritus: Slow IV 4-5mg/kg (0.1% solution) Administer over 20-30 mins 注射劑
局部麻醉劑
 
 
 
 
Local Anesthetics
Local Anesthetic Agent
Ropivacaine
Naropin
Infiltration/peripheral nerve block: <200mg  Caudal: 30-150mg  Brachial plexus block: 175-250mg  Stellate ganglion block: 10-20ml of  0.2 % solution  Paravertebral block: 3-4ml of  0.5% solution per segment  Epidural: Bolus  20-200mg, Infusion  4-15ml/hr  Spinal bolus: 15-22mg  Intrapleural: Bolus  <100mg, Infusion 5-7ml/hr, Intra-articular: <150mg, Max safe dose: 2.5mg/kg 注射劑
外科麻醉:硬膜外阻斷麻醉以進行外科手術,包括剖腹產及區域阻斷麻醉;急性疼痛處理:持續性硬膜外輸注或間歇性之一次注射給藥,如手術後或產後疼痛及區域阻斷麻醉 
 
 
 
 
Local Anesthetics
Local Anesthetic Agent
Tetracaine
Tetracaine
Spinal bolus/infusion: 5-20mg  Brachial plexus block: Combine 0.5-1.0mg/kg tetracaine with 30-50ml of  bupivacaine (0.25-0.375%) or lidocaine (1%) or mepivacaine Topical (spray): apply 2% solution for 1 seconds Max safe dose: 1.0-1.5mg/kg without epinephrine; 2.5mg/kg with epinephrine 注射劑
局部麻醉劑
 
 
 
 
Anti-arrhythmic agents
 
Adenosine
Adenocor
SVT: initial dose 6mg, if ineffective 12mg can be given 2 mins later and repeated again if necessary. 注射劑,凍晶注射劑
治療陣發性上心室心博過速、輔助診斷QRS波變寬或變窄之複雜性上心室心博過速                                  
 
 
dipyridamole, caffeine
 
Anti-arrhythmic agents
Antiarrhythmic agents
Mexiletine
Mexitil
Pain: initial 150-200mg (2-3mg/kg) qd-tid, maintenance 150-400mg (2-8mg/kg) qd-tid 持續性藥效膠囊,膠囊劑
心室性心律不整
 
theophylline
antacid, ammonium chloride, atropine, metoclopramide, phenytoin, rifampin, tobacco
digoxin
Anti-arrhythmic agents
Antiarrhythmic agents
Lidocaine iv
Lidocaine iv, xylocaine
Acute migraine: Sphenopalatine ganglion block slow IV 100mg or 2mg/kg administer over 20-30mins (5mg/min) Neuropathic pain/RSD: IM 200-400mg/week (4-6mg/kg) slow IV  50-300mg (1-5mg/kg of 0.1% solution) 注射劑,凍晶注射劑,凍膠,液劑
針劑:心室性不整律之急性治療。凍膠,液劑:表面麻醉
cimetidine
propranolol, amiodarone, succinylcholine
phenobarbital, procainamide
 
 
beta blocker agents
Metoprolol
Betaloc
Migraine prophylaxis:  initial 50mg bid, maintenance 50-100mg bid 錠劑,膜衣錠,持續性藥效膠囊
高血壓、狹心症                            
 
amiodarone, pentobarbital, rifampin, lithium
oral contraceptive agents
 
Anti-arrhythmic agents
beta blocker agents
Propranolol
Inderal
Migraine prophylaxis: initial 20mgqd-qid, maintenance 20-80mg qd-qid  Phantom pain: 80mg qd-tid 錠劑,膜衣錠,持續性藥效膠囊,注射劑
狹心症、不整律(上心室性不整律、心室性心搏過速)、原發性及腎性高血壓、偏頭痛、控制原發性震顫、控制焦慮性心搏過速、甲狀腺毒症的補助劑、親鉻細胞瘤
cimetidine, epinephrine, clonidine, insulin
chlorpromazine, cocaine, fluoxetine, furosemide, indomethacin, thyroid,tobacco, lidocaine, methyldopa, prazosin, theophylline, tubocurarine, verapamil, warfarine
alcohol, allergenic extracts, aluminum hydroxide, aminoglutethimide, aspirin, cholestyramine, desipramine, diatrizoate, ergotamine, flecainide, hydralazine, misoprostol, pravastatin, quinidine, acetaminophen, diazepam, fentanyl, isoniazid, procainamide
chlorpheniramine, tranylcypromine
Alpha-1 blocker
 
Prazosin
Minipress
Hypertension: oral dosing range  3-20mg daily, with usual oral dose 6 to 15mg daily in divided dose. 錠劑,膠囊劑
高血壓症、左心室衰竭、良性前列腺肥大                  
 
indomethacin, propranolol, digoxin
verapamil
 
Alpha-2 Agonist
Alpha-2 Agonist
Clonidine
Catapres
Migraine prophylaxis: 0.025-0.1mg bid-tid, Supplementation of analgesia: 0.025-0.1mg (0.05-0.4mg/day) bid-qid 錠劑,注射劑
高血壓                                 
propranolol
cyclosporine
naloxone, fluphenazine
rifampin
Calcium channel blockers
 
Diltiazem
Herbesser
Angina: initial 30mg qid, maintenance 180-360mg/day in 3-4divided doses Hypertension: initial 60-120mg bid, maintenance dose 240-360mg/day 錠劑,膜衣錠,持續性藥效膠囊,凍晶注射劑
狹心症、輕度至中度之本態性高血壓                    
cyclosporine
cisapride, amiodarone
insulin
 
Calcium channel blockers
 
Nicardipine
Perdipine
Angina/Hypertension: initial 20mg tid, maintenance 20-40mg tid 糖衣錠,膜衣錠,注射劑
高血壓                                 
 
 
 
 
Calcium channel blockers
Calcium channel blockers
Nifedipine
Adalat
Migraine prophylaxis: 10mg tid 錠劑,膜衣錠,持續性藥效膠囊,持續性藥效錠,膠囊劑,軟膠囊劑
高血壓、狹心症                             
 
cimetidine, phenytoin
ethanol, halothane, magnesium sulfate, tacrolimus
 
Calcium channel blockers
Calcium channel blockers
Verapamil
Verapamil
Migraine prophylaxis: 80-120mg tid 錠劑,膜衣錠,持續性藥效膠囊,持續性藥效錠,膠囊劑,注射劑
高血壓、狹心症                                
digoxin, quinidine
calcium gluconate, dantrolene, propranolol, rifampin, carbamazepine, lithium, theophylline, vecuronium
phenobarbital, sulfinpyrazone, etomidate, prazosin
 
 
Sympatholytic agents
Bretylium tosylate
Bretylium tosylate
IV regional sympathetic block: 1-2mg/kg dil. in 40-50ml 0.5% lidocaine or NS 注射劑
治療第一線抗心室不整律藥物無效時之心室不整律 
 
 
 
 
 
Sympatholytic agents
Guanethidine monosulfate
Ismedine
IV regional sympathetic block: 10-30mg (0.2-0.4mg/kg) dil. in 20-30ml NS or 0.5% lidocaine 錠劑,糖衣錠
中度及嚴重高血壓                            
chlorpromazine, desipramine, insulin
alcohol, dextroamphetamine, hydrochlorothiazide, minoxidil, phenelzine, phenylephrine
 
 
Corticosteroids
Corticosteroids
Dexamethasone
Dexamethasone
Bone pain/Neuropathic pain/Plexus pain: initial IV 16mg or PO 20-100mg, maintenance PO/IV 4-8mg q6h (1-2wks) then1-2mg bid 注射劑,膠囊劑,錠劑,糖衣錠,膜衣錠,糖漿劑,點眼劑,軟膏
急性風濕熱、風濕性關節炎、急性痛風性關節炎、支氣管氣喘血清病、散播性紅斑性狼瘡、結節性動脈周圍炎、過敏性皮膚炎、天皰瘡、關節囊炎、肌炎、纖維肌炎
aminoglutethimide
ephedrine, phenobarbital, phenytoin, interleukin-2
 
 
Corticosteroids
 
Hydrocortisone
Hydrocortisone
Intra-articular: Usual dose, hydrocortisone acetate suspension 5-75mg and depends on the size of the joint. Intralesional Usual dose, hydrocortisone acetate suspension 5-75mg and depends on the size of the area  to be injected. IM Usual dose, hydrocortisone sodium phosphate 15-240mg/day depending on the disease being treated. IV Usual dose, hydrocortisone sodium phosphate 15-240mg/day depending on the severity of the condition. Oral Usual dose, 20-240mg/day. 
      
乾粉注射劑,注射劑,滅菌懸液注射,乳膏劑,軟膏劑,點眼液劑,點眼膏劑,點耳鼻液劑,外用液劑
針劑:腎上腺皮質機能不全、劇烈休克、膠原疾病(全身性紅斑性狼瘡)過敏反應(支氣管氣喘)過敏性皮膚疾患(天皰瘡、剝脫性皮膚炎)。 外用:濕疹、接觸性皮膚炎、變位性皮膚炎、神經性皮膚炎、脂漏性濕疹、貨幣狀濕疹、急慢性濕疹、尋常性乾癬。 眼用:結膜炎、角膜炎、鞏膜炎、虹彩毛樣體炎、過敏性眼疾。                                                 
 
 
cholestyramine, pancuronium, theophylline
 
Corticosteroids
Corticosteroids
Methylprednisolone
Metisone,Solu-medrol
IV regional sympathetic block: 80mg dil. in 0.5% lidocaine or 50ml NS 凍晶注射劑,乾粉注射劑,注射劑,錠劑
針劑:腎上腺皮質機能不全、劇烈休克、支氣管性氣喘、膠原疾病、過敏反應、泛發性感染 口服:風濕性熱、風濕樣關節炎及過敏性症狀                                                      
 
aspirin, ketoconazole, troleandomycin
pyridostigmine
 
Corticosteroids
 
Prednisolone
 
Rheumatoid arthritis: 7.5mg or less may be used in patients with difficult-to-control rheumatoid arthritis. Short-term, high-dose bursts may also be to control flares of rheumatoid arthritis. 注射劑,膠囊劑,錠劑,糖衣錠,軟膏劑,點眼膏劑,點眼懸液劑
僂麻質斯性關節炎、過敏性疾患、皮膚疾患、膠原病             
 
cyclosporine, oral contraceptive agents, rifampin
isoniazid
 
Corticosteroids
 
Triamcinolone
Ledercort
Intra-articular: 2.5-5mg for smaller joints and 5-15mg for large joints injections into several joints up to a total of 80mg have been given  Intralesional: 3-48mg in divided amounts appropriate for the affected area  IM: 40-80mg Oral: 4-48mg daily 膠囊劑,錠劑,糖衣錠,乳膏劑,口內膏,滅菌懸液注射,注射劑
風濕性疾病、風濕性關節炎、風濕性心炎、急性風濕熱、痛風性關節炎、骨關節炎、愛迪生氏病、炎症性眼炎及支氣管喘息、過敏性皮膚病、濕疹、蕁麻症、迅發性紅斑性狼瘡疾患等膠原病
 
 
 
 
Anti-migraine agents
Ergot Alkaloids
Dihydroergotamine
Dihydergot
SC/deep IM 1mg then 1mg/1hr total dose 3mg 膠囊劑,錠劑
偏頭痛                                 
 
nitroglycerin
 
 
Anti-migraine agents
Ergot Alkaloids
Ergotamine
Ergomar
initial PO 2mg then 1-2mg/30min max 6mg, max 10mg/week 膠囊劑,錠劑,糖衣錠
血管性頭痛如偏頭痛、組織胺性頭痛                    
 
erythromycin
propranolol
 
Anti-migraine agents
Antiemetic agent
Metoclopramide
Primperan
10mg tid/ac and hs 注射劑,膠囊劑,錠劑,糖衣錠,膜衣錠,糖漿劑
預防嘔吐、逆流性消化性食道炎、糖尿病引起之胃腸蠕動異常         
 
cyclosporine, digoxin
atropine, levodopa, alcohol, carbamazepine, chlorothiazide, cimetidine, mexiletine, morphine, quinidine, succinylcholine
 
Anti-migraine agents
Migraine Abortive
Sumatriptan
Imigran
PO: 25-100mg, max 300mg/24hr 膜衣錠
有先兆或無先兆偏頭痛發作之急性緩解。本藥僅適用於有明確診斷之偏頭痛  
 
 
 
 
 
Migraine Abortive
Zolmitriptan
Zomig
PO: 2.5mg, max 10mg/24hr 錠劑
有先兆或無先兆偏頭痛發作之急性緩解。本藥僅適用於有明確診斷之偏頭痛  
 
 
 
 
Anti-viral Agents
Anti-viral Agents
Acyclovir
Zovirax
Herpes simplex: PO 200mg q4h×10 days  Herpes zoster: PO  800mg q4h×7-10 days 錠劑,注射劑,乳膏劑,軟膏劑,懸液劑
帶狀庖疹病毒引起之感染、單純庖疹病毒引起之皮膚及粘膜感染、預防骨髓移植及白血病所引之免疫不全病人之單純庖疹感染、復發性單純庖疹感染之抑制,水痘感染
 
 
probenecid, lithium, zidovudine
 
Anti-viral Agents
 
Famciclovir
Famvir
Herpes zoster: PO  500mg q8h×7 days  Recurrent genital HSV: PO 125mg bid×5 days 膜衣錠
帶狀庖疹及生殖器庖疹急性感染、抑制反覆性生殖器庖疹復發                                            
 
 
 
 
Anti-viral Agents
 
Valaciclovir
Valtrex
Herpes Zoster: 1gm 3 times per day for 7 days  Genital herpes: initial episodes: 1gm orally twice daily for 10days  Recurrent episodes: 500mg twice a day for 3 days with or without meals  Suppressive therapy: 1gm once daily 錠劑
帶狀庖疹、復發性生殖器庖疹                      
 
 
 
 
NMDA Antagonists
 
Amantadine
PK-Merz
Prophylaxis influenza A: 200mg/day in 1-2 divided doses×10days  Treatment influenza A: 200mg/day  in 1-2divided doses starting within 24-48h after onset of illness and continuing for 24-48h after symptoms disappear Parkinaon`s disease: initial 100mg/day, max 400mg/day in 2divided doses 膠囊劑,錠劑,內服液劑,糖漿劑,注射劑
帕金森氏病、預防及治療A型流行性感冒症狀                
 
 
hydrochlorothiazide/triamterene
 
NMDA Antagonists
NMDA receptor Antagonists
Dextromethorphan
Medicon
PO: 10-240mg/day in divided doses 錠劑,糖漿劑
鎮咳、袪痰(咽頭炎、喉頭炎、支氣管炎、支氣管擴張症、支氣管氣喘所引起之咳嗽及喀痰)                               
 
paroxetine
 
 
NMDA Antagonists
 
Ketamine
Ketalar
induction of dissociative anesthesia: recommended doses IV 1-4.5 mg/kg or IM 6.5-13mg/kg, maintenance of anesthesia  IV infusion of 0.1-0.5mg/mins or one-half to the full induction dose IV or IM, repeated as required.  Sedation and analgesia: IM 2-4 mg/kg or IV doses of 0.2-0.75 mg/kg
注射劑
全身麻醉
 
diazepam, halothane, tubocurarine
thyroid, aminophylline
 
NMDA Antagonists
 
Magnesium sulfate inj.
Magnesium sulfate
Seizures of Toxemia of pregnancy: 4-5gm magnesium sulfate in 250ml of dextrose 5% in water or normal saline and infusing over 30mins. Simultaneously, an intramuscular injection of up to 10gm magnesium sulfate  Hypomagnesemia: magnesium sulfate 5gm may be added to one liter of 5% dextrose or 0.9% sodium chloride for slow infusion over 3 hrs. 注射劑
產驚、產驚前、孕婦尿毒、產科全身麻醉輔助                
 
vecuronium
 nifedipine
 
Controlled Drugs
Potent opioid analgesics
Alfentanil
Rapifen
Analgesia: IV/IM 250-500μg (5-10μg/kg) 注射劑
短效麻醉性止痛劑及麻醉誘導劑。 
 
erythromycin
 
 
Controlled Drugs
Potent opioid analgesics
Buprenorphine
Temgesic
Analgesia: IV/IM  0.3-0.6mg (6-12μg/kg) q6-8h 舌下錠,注射劑
中、重度疼痛。                             
 
 
 
 
Controlled Drugs
Potent opioid analgesics
Fentanyl patch
Durogesic TTS
Pain: initial 25-50μg/hr, maintenance 25-100μg/hr 穿皮貼片劑
需要使用鴉片類製劑控制的慢性疼痛。
 
 
propranolol( fentanyl system)
 
Controlled Drugs
Potent opioid analgesics
Meperidine
Demerol
Pain: PO/IM/SC  50-150mg (1-3mg/kg) q3-4hr 錠劑,注射劑
鎮痛                                  
phenelzine
chlorpromazine
phenobarbital, phenytoin, isoniazid
 
Controlled Drugs
Potent opioid analgesics
Morphine
MST continus, MSSR
Pain: PO 10-60mg q4h, extended release 15-200mg q12h 錠劑,膜衣錠,持續性膜衣錠,注射劑,酊劑,散劑
鎮痛,解除癌症末期病患之嚴重疼痛                                    
 
cimetidine, thiopental, tubocurarine
amitriptyline, metoclopramide
 
 
Potent opioid analgesics
Pentazocine
Taiwin(R) NX
Analgesia: PO 50-10mg (1-2mg/kg) q3-4hr, max 600 mg/day 錠劑
中度至嚴重疼痛之緩解 
 
 
 
 
 
Potent opioid analgesics
Sufentanil
Sufenta
Pain:IV/IM 10-30μg (0.2-0.6μg/kg) 注射劑
麻醉鎮靜劑 
 
 
 
 
Controlled Drugs
weak opioid analgesics
Codeine
Codeine
Anagesia: PO/IM/IV 15-60mg (0.5mg/kg) q4h, max 120mg/day 錠劑,注射劑,糖漿劑
鎮咳、鎮痛                               
 
 
 
 
 
weak opioid analgesics
Oxycodone HCl
Oxycodone hydrochloride
Anagesia: PO  5-10mg q4-6h, SR 10-80mg q12h 注射劑
鎮痛 
 
 
 
 
Controlled Drugs
weak opioid analgesics
Propoxyphene
Depain X
Anagesia: PO 65mh q4h, max 390mg/day 膠囊劑
解除輕度-中度疼痛                           
 
alcohol, carbamazepine, warfarin
amphetamine, charcoal, doxepin
orphenadrine
Controlled Drugs
Narcotic Antagonist
Naloxone
Narcan
narcotic depression or drug over dose: 0.1-2mg, may repeat at 2-3mins interval 注射劑
麻醉藥品過量之解毒劑                          
 
 
captopril, clonidine
 
Controlled Drugs
Topical Anesthetic
Cocaine
Cocainse hydrochloridum
Topical: 1mg/kg (1-4% solution) Nasal: 1-2ml each nostril (1-4% solution)  Concentrations greater than 4% are not advisable and increase potential for systemic toxic reactions. Max safe dose 1.5mg/kg 原料藥
局部麻醉劑 
 
propranolol
 
 
other
Bisphosphonate
Alendronate
Fosamax
Treatment of osteoporosis/Metastatic bone pain: 10mg qd 錠劑
停經婦女骨質疏鬆症之治療                       
 
 
 
 
other
 
Glucosamine
Viartril-S
Osteoarthritis: PO 500 mg tid. 膠囊劑
因骨關節代謝機能衰退引發之關節病如頸關節炎、骼關節炎、肩胛關節炎、膝關節炎、背關節炎、骨質疏鬆、骨膜硬化、腰痛、骨折、骨關節營養不良、慢性及亞急性關節炎
 
 
 
 
other
 
Prostaglandin E1
Hemabate, Prostin
IV: peripheral obstructive arterial disease: 14-21ng/kg/min of alprostadil for 3 days, once a week for three weeks. Raynaud's phenomena: 6-10 ng/kg/min introvenously for 12-72 hrs 注射劑,凍晶注射劑
用於先天性心臟缺損之新生兒緩解但非最終的治療,此療法可以暫時維持動脈導管之開放至矯正手術施行為止,(先天性心臟缺損包括肺閉鎖,肺狹窄,三尖瓣閉鎖,法祿氏四疊症,主動脈弓中斷,主動脈狹窄或伴有無其他缺陷之大血管轉位)                       
 
 
 
 
other
Local anesthetic Agent
Lidocaine/Prilocaine
EMLA cream
Minor dermal procedures: Topical   apply 2.5g of Emla cream over 20-25 cm2 of intact skin and cover with occlusive dressing for at least 45 mins. Neonatal circumcision: Topical  apply 0.5-1.0g of EMLA cream over surgical site and cover with occlusive dressing for at liast 60-80 mins prior surgery. Major dermal procedures: Topical  Apply 2g of EMLA cream per 10cm2 of intact skin and cover with occlusive dressing for at least 2 hrs. Max recommeded dose: 60g  Max recommended area <10kg: 100cm2, 10-20kg: 600cm2, >20kg: 2000cm2 Max recommended duration: 4hrs 乳膏劑
與下列狀況有關的皮膚表面止痛:1.插針,如靜脈注射導管或抽血前 2.表皮外科處置 3.生殖器粘膜,如表皮外科處置前或浸潤麻醉前
 
 
 
 
other
 
Vagostigmin
Vagostigmin
Myasthenia gravis: 15-375mg daily (individualize frequency); 0.5mg SC/IM, Neuromuscular blockade reversal: 0.5-2mg IV, repeat PRN; usually than 5mg needed 注射劑,點眼液劑
針劑:排尿困難, 眼用:眼球肌肉症狀之改善                           
 
 
 
 
other
 
Hyoscine-N-butylbromide
Buscopan
Antispasmodic or antidysmenorrheal: PO 10-20mg, 3 to 5 times daily. Rectal 1-2 supp 3 to 5 times daily, Parenteral 10-40mg , up to a max daily dose of 100mg. 糖衣錠,錠劑,膠囊劑,注射劑
胃腸痙攣及運動亢進、膽管痙攣及其運動障礙、尿路痙攣、女性生殖器之痙攣症狀                                   
 
 
 
 
 
 
Benzbromarone
Deuron, Urinorm
PO: 50-200mg daily 錠劑,膠囊錠
痛風、高尿酸血症                          
 
 
 
 
 
 
Hyaluronate sodium
ARTZ/-ARTZ DISPO
Intra-articular: Usual dose  20 mg/week× 5

      
注射劑
限用於保守性非藥物治療無效及一般鎮痛劑如ACETAMINOPHENE,治療無效之退化性膝關節炎疼痛患者 退化性關節炎、肩關節周圍炎、慢性風濕性關節炎
 
 
 
 
other
 
Tamoxifen
Nolvadex
Breast cancer: premenopausal patient 20mg bid, postmenopausal patient 10mg bid 錠劑
轉移性乳癌之治療、乳癌手術後之輔助療法。乳房疼痛                
 
warfarin
 
 
other
 
Clodronate
Bonefos
Hypercalcemia: PO 2400-3200mg/day in 3-4divided doses, IV infusion 3-5mg/kg during 3-5 consecutive days 膠囊劑,膜衣錠,注射劑
惡性腫瘤之蝕骨性骨頭轉移、惡性高血鈣症
 
 
 
 
other
 
Nitroglycerin
Nitrostst
Acute angina: sublingual tab (0.15 to 0.6 mg) or translingual spray (0.4 mg) may be repeated every 5 mins until relief occurs or 3 doses have been taken, Prophylaxis of anticipated (stress or exertion induced) attacks: sublingual tab 0.15 to 0.6 mg, translingual spray 0.4 mg, or transmucosal tab 1 mg can be used, Chronic prophylaxis: transmucosal, transdermal, or sustained release dosage forms are preferred. IV doses of 5 mcg/min should be initiated as a continuous infusion, with titration to response as needed 錠劑,持續性藥效膠囊,穿皮貼片劑,貼片劑,注射劑,口腔噴液劑
狹心症之預防及治療                           
 
alteplase, dihydroergotamine, heparin
aspirin, indomethacin, pancuronium
 
other
 
Calcitonin
Miacalcic
Paget`s disease: initial 100IU/day, maintenance 50IU or 50-100IU 3 times weekly  Hypercalcemia: 4-8IU/kg q12h, max 8IU/kg q6h  Postmenopausal Osteoporosis: 100IU/day 注射劑,鼻用氣化噴霧,鼻用噴液劑
高血鈣危象、骨骼的帕哲特氏病(PAGETS DISEASE OF BONE) 斷經後(POST-MENOPAUSAL)引起之骨質疏鬆      
 
 
 
 
other
 
Capsaicin ointment
Capsaicin
apply thin film  tid-qid daily 乳膏劑
暫時緩解局部疼痛
 
 
 
 
other
Central-Acting Analgesic
Tramadol
Tramal
Analgesia: PO 50-10mg (1-2mg/kg) q4-6hr, max 400mg/day 膠囊劑,持續性藥效錠,注射劑
中度至嚴重和急慢性疼痛                         
 
 
 
 
other
 
Somatostatin
Somatosan
initial 250μg IV bolus,  maintenance 250μg/hr (3.5μg/kg/hr) IV infusion 凍晶注射劑,注射劑
食道靜脈曲張引起的嚴重急性出血。嚴重急性消化性潰瘍出血,於急性之糜爛或出血性胃炎之急性嚴重出血,胰臟手術後胰臟併發症之預防         
 
 
 
 
other
 
Danazol
Danazol
Endometriosis: 200-800mg/day in 2 divided doses  Fibrocystic Breast disease: 100-400mg/day in 2 divided doses  Hereditary Angioedema: initial 200mg in 2-3 divided doses 錠劑,膠囊劑,腸溶錠
子宮內膜異位症、早發春機發動、囊狀慢性乳腺炎、乳腺肥大、乳痛、月經過多、纖維性囊腫性乳房疾病                          
 
carbamazepine
 
 
Muscle relaxants
Antispasm
Baclofen
Befon
Spasticity/Trigeminal neuralgia/Organic headache/Neuropathic pain: initial PO 5-10mg tid, maintenance PO 5-25mg qid 錠劑
限於脊髓和大腦疾病或損傷引起的肌肉痙攣。                
 
 
 
 
 
Antispasm
Botulinum toxin type A
Dysport
Blepharospasm: initial recommended doses is 1.25 to 2.5 units injected into the medial and lateral pre-tarsal orbicularis oculi of the upper lid and into the lateral pre-tarsal orbicularis oculi of the lower lid. A 27- to 30- garge needle, without electromyographic guidance, is recommended for the infections. The maximum clinical effect is observed at 1 to 2 weeks post-treatment and lasts approximately 3 months.Hemifacial spasm: no standard dose has been established for initial and subsequent doses. 乾粉注射劑
眼瞼痙攣,半邊顏面痙攣,痙攣性斜頸,斜視,局部肌肉痙攣症,小兒腦性麻庳引起之肌肉痙攣
 
 
 
 
 
Antispasm
Clonazepam
Rivotril
Pain: initial dose 0.25mg bid, increasing to 1mg/day after 3 days, maintenance dose 1mg/day 錠劑
癲癇
 
 
Carbamazepine, phenelzine,valproic acid
primidone
 
Antispasm
Clonidine
Catapres
Premedication: PO 0.1-0.3mg (3-5μg/kg) Migraine prophylaxis: 0.025-0.1mg bid-tid Supplementation of analgesia: PO 0.025-0.1mg bid-qid (0.05-0.4/kg)/day 錠劑,注射劑
高血壓                                 
propranolol
cyclosporine
naloxone, fluphenazine
rifampin
Muscle relaxants
 
Chlorzoxazone
Solaxin
Muscular conditions: 250mg tid-qid  Severe muscle spasms: 500-750mg tid-qid 錠劑,膠囊劑,腸溶錠
肌肉緊張症、急性腰痛、脊椎間板症候群及脊髓炎痙攣、神經肌肉之機能異常等所伴生有肌痙攣、強直之諸疾患                       
 
 
 
 
 
Antispasm
Methocarbamol
Methocarbamol
Musculoskeletal pain: initial PO 1500mg qid for 2-3days, max 3g/dy for 3days, maintenance PO 750mg q4h or 1000mg q6h or 1500mg tid 錠劑,注射劑
對於急性肌肉疼痛緩解之輔助治療劑                    
 
 
 
 
Muscle relaxants
 
Orphenadrine
Norflex
Acute skeletal muscle relief: PO 100mg bid, IV/IM 60mg bid 錠劑,注射劑
骨骼肌鬆弛劑                              
 
 
levodopa/benserazide
propoxyphene
Muscle relaxants
Antispasm
Tizanidine
Sirdalud
Spasticity/Trigeminal neuralgia/Organic headache/Neuropathic pain: initial PO 2mg bid, 4mg hs, maintenance PO 4-12mg tid 錠劑
神經疾患所引起之痙攣症狀、疼痛性肌肉痙攣                                                   
 
 
 
 
 
H1 receptor antagonist
Hydroxyzine HCl
Vistaril
Pain: 25-100mg (0.5-2.0mg/kg) q6-8h 糖衣錠,錠劑,膜衣錠
焦慮狀態、嘔吐、過敏疾患                        
 
 
 
 
 
H2 receptor antagonist
Cimetidine
Tagamet
PO 300mg (7.5mg/kg) q6-8h, alternately 400-1600mg hs 注射劑,錠劑,膜衣錠
十二指腸潰瘍、胃潰瘍、消化性食道炎、上胃腸道糜爛或潰瘍引起之出血、再發性潰瘍、孔性潰瘍、膽囊纖維變性併發有胰臟功能不全時之補助療法。有鈣化現象(Calcinosis)的五十肩       
lidocaine, phenytoin, propranolol, theophylline, warfarin
carbamazepine, carmustine, clozapine, diazepam, flecainide, glipizide, imipramine, ketoconazole, morphine, nifedipine, procainamide, quinidine, succinylcholine
antacid, metoclopramide, propantheline, alcohol, cefotaxime, chlormethiazole, chloroquine, clomiphene, digoxin, dobutamine, erythromycin, ferrous sulfate,  fluorouracil, indomethacin, metronidazole, moricizine, paroxetine, phenobarbital, tetracycline, triamterene, valproic acid, venlafaxine
buspirone
 
H2 receptor antagonist
Famotidine
Gaster
PO 20mg bid or 20-40mg hs 注射劑,錠劑,膜衣錠,糖衣錠,凍晶注射劑
胃潰瘍、十二指腸潰瘍、吻合部潰瘍、上部消化管出血(消化性潰瘍、急性STRESS潰瘍、出血性胃炎而引起的)、逆流性食道炎、ZOLLINGER-ELLISON
 
 
 
 
 
H2 receptor antagonist
Ranitidine
Zantac
PO 150mg bid, altermately 150-300mg hs 注射劑,錠劑,膜衣錠
良性胃潰瘍、十二指腸潰瘍、回流食道炎、邊緣性之消化性潰瘍、高濃度胃酸分泌症候群。                                
 
 
sucralfate
 
 
Antiulcer agents
Misoprostol
Cytotec
PO 100-200mg qid 錠劑
胃及十二指腸潰瘍                            
 
 
antacid, phenylbutazone, propranolol
 
 
Antiulcer agents
Sucralfate
keal
PO 1g bid-qid 錠劑,內服顆粒劑,懸液用顆粒劑,細粒劑,懸液劑,咀嚼錠
胃潰瘍、十二指腸潰瘍                         
 
norfloxacin, phenytoin
ketoconazole, levothyroxine, ranitidine, theophylline, warfarin
chlorpropamide
 
Antiemetic agent
Hydroxyzine HCl
Vistaril
Pain: PO/IM 25-100mg (0.5-2.0mg/kg) q6-8h 膠囊劑,糖衣錠,錠劑,膜衣錠
焦慮狀態、嘔吐、過敏疾患                        
 
 
 
 
 
Antiemetic agent
Metoclopramide
Primperan
PO 10mg 30mins before meals and hs 注射劑,膠囊劑,錠劑,糖衣錠,膜衣錠,糖漿劑
預防嘔吐、逆流性消化性食道炎、糖尿病引起之胃腸蠕動異常         
 
cyclosporine, digoxin
atropine, levodopa, alcohol, carbamazepine, chlorothiazide, cimetidine, mexiletine, morphine, quinidine, succinylcholine
 
 
Antiemetic agent
Ondansetron
Zofran
Postoperative nausea: PO 8-16mg 1hr before induction of anesthesia, Slow IV 4 mg over 1-5mins immediately before induction of anesthesia or postoperatively 注射劑,膜衣錠
細胞毒性化學療法及放射線療法所致之噁心及嘔吐,以及手術引起之噁心、嘔吐
 
 
 
 
 
Antiemetic agent
Prochlorperazine
Novamin
Antiemetic/Pain: PO 5-10mg tid-qid,  IV/IM 5-10mg (5mg/ml/min) 糖衣錠,錠劑,注射劑
精神病狀態、噁心、嘔吐                         
 
 
 
 
 
Antiemetic agent
Promethazine
Pyrethia
Antiemetic/Sedative/Analgesic adjunct: IV/deep IM/PO 12.5-50mg 糖衣錠,錠劑,注射劑
震顫麻痺、巴金生徵候群、麻醉前投藥、人工(藥物)冬眠、伴有感冒等上氣道炎之噴嚏、流鼻水、咳嗽、過敏性鼻炎、枯草熱、血管運動性浮腫、伴有皮膚疾患之搔癢(溼疹、皮膚炎、皮膚搔癢症、藥疹、中毒疹) 蕁痲疹、動暈病
 
 
 
 
 
Cardiopulmonary resuscitation
Atropine
Atropine
Sinus bradycardia and CPR: IV/IM/SC 0.4-1.0mg  Premedication: IV/IM 0.4-1.0mg, PO 0.4-0.6mg q4-6h 注射劑,點眼液劑
膽石症、幽門痙攣、胃酸過多、胃痙攣、有機磷化物、毛果芸香鹼中毒、診斷用散瞳、調節痙攣、乙醚等麻醉時之抑制支氣管分泌               
 
 
metoclopramide, mexiletine
 
 
Cardiopulmonary resuscitation
Bretylium tosylate
Bretylium tosylate
IV regional sympathetic block: 1-2mg/kg dil. in 40-50ml 0.5%lidocaine or NS 注射劑
治療第一線抗心室不整律藥物無效時之心室不整律 
 
 
 
 
 
Cardiopulmonary resuscitation
Epinephrine
Epinephrine
Test dose in reginal anesthesia: marker for accidental intravascular injection:10-15μg 2-3ml of 1:200,000 epinephrine solution mixed with local anesthetic  Prolongation of infiltration/plexus/epidural/cauda/ interpleural anesthesia: 1:200,000 to 1:100,000 solution mixed  with local anesthetic. Prolongation of spinal anesthesia: 0.1-0.4mg (0.1-0.4ml of a 1:1000 solution) added to anesthetic spinal fluid mixture 注射劑,點眼液劑
過敏反應引起之休克、呼吸道痙攣或喉道水腫、心跳停止之急救、支氣管性氣喘 
halothane, propranolol
imipramine
insulin
 
 
Cardiopulmonary resuscitation
Lidocaine
Lidocaine
Acute migraine: Sphenopalatine ganglion block slow IV 100mg or 2mg/kg administer over 20-30mins (5mg/min) Neuropathic pain/RSD: IM  200-400mg/week (4-6mg/kg) slow IV  50-300mg (1-5mg/kg of 0.1% solution) 注射劑,凍晶注射劑,凍膠,液劑
針劑:心室性不整律之急性治療。凍膠,液劑:表面麻醉
cimetidine
propranolol, amiodarone, succinylcholine
phenobarbital, procainamide